Benefits of cortisone in assisted reproduction techniques

The therapeutic strategy for the immunological causes of infertility is still under discussion due to the low therapeutic response and the high costs of treatment, such as the use of intravenous immunoglobulins , Intralipid and microimmunotherapy fertility doctor singapore.

Cortisone is a corticosteroid hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. The extremely cheap drug is rapidly absorbed in the intestine; its anti-inflammatory action , which differs from that of non-steroidal anti-inflammatory drugs ( NSAIDs), works by blocking the synthesis of proinflammatory prostaglandins, which are responsible for regulating body temperature, erythema, edema and increased sensitivity to pain and the synthesis of proinflammatory leukotrienes that cause bronchoconstriction.

It is successfully used for diseases such as anaphylactic shock, allergies, asthma, multiple sclerosis, rheumatological autoimmune diseases such as rheumatoid arthritis and connective tissue diseases, dermatological diseases such as psoriasis, muscular such as myositis, intestinal such as Crohn’s disease or ulcerative colitis and finally for the rejection of transplants, representing for many patients a real life-saver.uterine mucosa through a mechanism of angiogenesis (creation of new blood vessels).

The presence of anti-phospholipid antibodies, such as anticardiolipin antibodies (ACA) and anti-Lupus antibodies (LAC), inhibits this mechanism causing venous and arterial thrombosis with a consequent risk of miscarriage.

What are the benefits of time-lapse in assisted reproduction therapy?

Initially, it enables us to trace the embryo in actual period without having to eliminate it from the incubator to look at it under a microscope. This allows us to obtain better quality embryos without changing their culture conditions. Secondly, by having a video of the entire development of the embryos, embryologists have at our disposal a series of selection tools that allow us to choose the best embryos to transfer.